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Phosphatidylserine (PS)

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Mind Lab Pro®
Phosphatidylserine (PS) 100 mg
as Sharp-PS® Green

Phosphatidylserine (PS) is a phospholipid highly concentrated in the brain, where it optimizes the formation and function of brain cell membranes. PS may be the most evidence-backed nootropic for memory.*

Brain Support

  • Promotes formation of fluid, healthy brain cell membranes*
  • Optimizes brain cell membrane function, including neurotransmission*
  • Helps with brain cell regeneration, maintenance and repair*
  • Required for the production of brain cells' myelin sheaths*

Nootropic Effects

  • Supports short- and long-term memory performance*
  • Promotes learning and recall*
  • Maintains clarity, mood, concentration and focus*
  • May help with mild memory issues associated with aging*

Mind Lab Pro®'s Phosphatidylserine as Sharp-PS® Green

  • Sharp-PS® Green is premium branded phosphatidylserine derived from natural sunflower lecithin; a 100% soy-free PS supplement
  • Sharp-PS® Green is made with a patented, eco-friendly process
  • Mind Lab Pro®'s 100 mg Sharp-PS® Green dosage > many standalone PS supplements

Why Mind Lab Pro® includes PS


Phosphatidylserine (PS) is a phospholipid building block compound that is used to form cell membranes throughout the body. PS is most concentrated in the brain, where it comprises 15% of total phospholipids.<1>

In the brain, PS plays two important roles for healthy growth and function that may have far-reaching effects on overall brainpower:

  1. PS helps keep brain cell membranes fluid and flexible. Healthy cell membranes perform dynamically, directing cell-to-cell communications and more.<2>  In optimizing brain cell membranes, PS supports the neurotransmission that drives all types of thinking and memory<3>
  2. PS supplies a key phospholipid building block that is required for brain regeneration, building and repair, including neurogenesis, brain plasticity and myelin sheath formation.<4,5>

PS is Mind Lab Pro®’s flagship nootropic for memory performance, but its complex roles in brain cell membrane processes may enhance all types of thinking while optimizing long-range brain health.

In a literature review published in 2015, researchers suggested that PS appears to support various human cognitive functions, including:<6>

  • Formation of short-term memory
  • Consolidation of long-term memory
  • Memory creation and retrieval
  • Attention and concentration
  • Reasoning and problem solving
  • Language and communication skills

How Phosphatidylserine (PS) may help with brain health and mental performance

Brain Regeneration

PS is a building block phospholipid nutrient that helps with brain cell creation, maintenance and repair. It is especially important for the formation of cell membranes. Decline of phospholipids like PS in brain cell membranes has been linked with brain degeneration, including age-related cognitive decline.<7>

Brain Protection

When brain cells shut down, they become toxic. PS sends out a signal that alerts the immune system to collect and dispose of the degrading brain cells before they turn dangerous – helping to protect neighboring cells from toxic damage.<8,9>

PS has also been suggested to help protect brain and body from the negative effects of stress, potentially by blunting release of the stress hormone cortisol.<10>  PS's anti-stress effects have been suggested to assist with mood and mental clarity.<11>

Brain Energy

One human study linked PS supplementation to a significant increase of brain glucose metabolism, including a 20.3% increase in the basal ganglia/thalamus and a 19.3% increase in the visual cortex.<12>

Brain Chemicals

Animal research suggests PS helps stimulate acetylcholine neurotransmitter production. PS’s support for brain cell membrane function may further help brain chemicals; healthy cell membranes facilitate healthy neurotransmission.<13>

Phosphatidylserine (PS) is the only nootropic with an FDA-qualified health claim, which reads:

  • "Phosphatidylserine (PS) may reduce the risk of cognitive dysfunction in the elderly. Very limited and preliminary scientific research suggests that PS may reduce the risk of cognitive dysfunction in the elderly. FDA concludes there is little scientific evidence supporting this claim.*"

Mind Lab Pro® Stack Strategy: Phosphatidylserine (PS) + Rhodiola Rosea for Competitive Cognition in Sports

PS is often associated with age-related memory benefits, but may be emerging as a nootropic sports nutrient. Research has linked PS to a reduction in perceived stress that improved golf scores; as well as improved resistance to exercise-induced stress that extended time to exhaustion during training.<14,15>

Rhodiola rosea is another nootropic that strengthens stress resistance and enhances athletic performance. Rhodiola has been used traditionally by Russian athletes in powerlifting and biathlon competitions, and has been shown to improve the body's ability to adapt to exercise.<16>

  • Together in Mind Lab Pro®, the nootropics PS and Rhodiola combine to support the healthy stress responses and mental clarity that help contribute to peak performance during athletic competition.

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

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The statements on this page have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent disease.