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Does Citicoline Increase Dopamine?

By Abigail Roberts | |

Citicoline does not increase dopamine, but it does increase acetylcholine - the chief neurotransmitter of the parasympathetic nervous system.

If you’re looking for a nutrient that does increase dopamine, the amino acid L-Tyrosine does just that. This is one of the key ingredients in Mind Lab Pro, the best nootropic on the market.

So, how does L-Tyrosine play a role in synthesizing dopamine? How does citicoline work? Is it possible to stack these two potent compounds to obtain enhanced nootropic effects?

All questions answered here!

What Does Citicoline Do?

Citicoline, also known as CDP-choline, is a nootropic compound offering cognitive-enhancing properties.1

Citicoline delivers the two compounds choline and cytidine to the brain. Choline is a nutrient found in many foods, and is needed for the regulation of memory, mood, muscle control and many other functions.

Elevated levels of citicoline will in turn increase acetylcholine, which is the main neurotransmitter involved in most executive functions including speech, focus and working memory.

An increase in citicoline will also increase levels of phosphatidycholine, which is the building block of brain cells.

Thus, taking citicoline would promote enhanced brain function, as well as long-term brain cell health.

The Nootropic Effects of Citicoline

Citicoline enhances mental performance without the crash of stimulants such as caffeine, thus:

  • Promoting mood balance
  • Improving focus, concentration, and attention
  • Improving memory
  • Maintaining healthy brain function
  • Fighting against age-related mental decline

So, while citicoline doesn't have much to do with dopamine, what other nootropic compounds can actually help increase dopamine?

Increasing Dopamine: L-Tyrosine 101

You may have heard of dopamine as the “feel-good” hormone. This important chemical messenger plays a significant role in our brain's reward system, which is precisely why it is often associated with pleasure.

You may be familiar with the pleasurable feeling you get when you are listening to your favorite music, finishing a challenging workout, or waking up after a glorious night's sleep - this is the feeling of dopamine being released!

Dopamine also affects other behaviors such as attention, motivation, mood, and learning.

So, what role does L-tyrosine play in boosting our dopamine levels?

L-tyrosine is an amino acid used to synthesize neurotransmitters involved in memory, mood, and mental processing, such as dopamine.

Some studies have noted that L-tyrosine may help promote working memory and optimize mental performance under high-stress, multitasking conditions.

L-tyrosine is also becoming more popular for its nootropic effects, which is why it’s a key ingredient in many of the best nootropic formulas.

Mind Lab Pro: Nootropics for Dopamine

Seeking something to boost your dopamine levels, as well as your overall cognitive function and brain health? Let’s take a closer look at some of the key ingredients in Mind Lab Pro!

N-Acetyl L-Tyrosine

This is the active form of L-tyrosine, the big player involved in replenishing neurotransmitters such as dopamine.

L-tyrosine helps counteract that stressed, burnt-out feeling you get when you’re attempting to juggle multiple responsibilities. Increased L-tyrosine results in increased motivation, improved working memory, and better moods.


L-theanine is thought to indirectly increase dopamine, as well as serotonin and GABA, the other neurotransmitters involved in mood and overall wellbeing.

L-theanine is an anxiolytic amino, helping to relax you while sustaining focus, attention, and motivation.


Vitamins B6, B12, and folate may help neurotransmitter metabolism too.

Most notably B6, which is involved in regulating our mood and cognitive function by synthesizing the neurotransmitters dopamine, GABA, serotonin, noradrenalin, and histamine.2

Thus, B6 helps increase dopamine levels, decreasing symptoms of anxiety, depression, and fatigue.

These are just a few potent ingredients in Mind Lab Pro that can help increase dopamine levels.

The other ingredients contained in Mind Lab Pro are some of the most effective natural nootropics, enhancing cognitive function and promoting overall brain health.

Take-Home Message: Does Citicoline Increase Dopamine?

While citicoline does not increase dopamine, it does increase acetylcholine, a different, though very important, neurotransmitter.

Citicoline energizes our brain cells and enhances mental performance, promoting mood balance, improving memory and function, and maintaining healthy brain function.

L-tyrosine, among L-theanine and B-vitamins, are the key nootropic ingredients in Mind Lab Pro that help increase dopamine levels, making Mind Lab Pro the best nootropic for improving mood, concentration, focus, and attention, with minimal side effects.


  1. K. Patel. CDP-choline. Examine.com. 2021
  2. Clayton PT. B6-responsive disorders: a model of vitamin dependency. J Inherit Metab Dis. 2006 Apr-Jun;29(2-3):317-26.

These statements have not been approved by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

This article is an opinion and explanation of current research given by the author. It is not an expression of a medical diagnosis or treatment and should not be relied on as such.

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