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N-Acetyl L-Tyrosine

By Dave Wright | |

Mind Lab Pro® supplies:
N-Acetyl L-Tyrosine 175 mg

N-Acetyl L-Tyrosine is a master precursor amino acid used to synthesize neurotransmitters involved in memory, mood and mental processing, including dopamine, epinephrine and norepinephrine.*

Brain Support

  • Supports neurotransmitters that are depleted by stress*
  • May help protect the brain against stress hormones*

Nootropic Effects

  • Promotes working memory under multitasking conditions*
  • Supports alertness, mood and sharp mental clarity*
  • Optimizes mental performance in times of fatigue*

Mind Lab Pro® N-Acetyl L-Tyrosine

  • N-Acetyl L-Tyrosine (NALT) is a preferred Tyrosine form for brain health
  • NALT may have bioavailability advantages over plain L-Tyrosine

Why Mind Lab Pro® includes N-Acetyl L-Tyrosine

Stress drains brainpower. Part of the reason why: Stress notably depletes catecholamine brain chemicals and the L-Tyrosine that is needed to create them.<1,2>

Low catecholamine levels make the brain even more susceptible to the negative effects of stress, which drives brain chemicals down further in a vicious cycle. Unbalanced catecholamine levels are associated with brain degeneration and problems with attention.<3,4>

  • Mind Lab Pro® supplies N-Acetyl L-Tyrosine to reverse stress-induced catecholamine neurotransmitter depletion and restore sharp mental performance under stress, multitasking, sleep deprivation and other challenging conditions.<5>

N-Acetyl L-Tyrosine is Mind Lab Pro®’s flagship nootropic for countering the negative cognitive effects of stress. Research has shown L-Tyrosine helps to promote:

  • Memory function and learning speed during cold water immersion<6>
  • Enhanced mental performance during loud 90 decibel noise exposure<7>
  • Working memory during demanding multitasking activities<8>
  • Cognitive performance and mood during sleep deprivation<9>

While its nootropic effects may center on dynamic mental processing under stress, NALT’s far-reaching support for brain chemicals expands to support other aspects of cognition across all populations, making it an ideal ingredient for Mind Lab Pro®’s Universal Nootropic™ formula.

How N-Acetyl L-Tyrosine may help with brain health and mental performance

Brain Chemicals

Animal research has shown L-Tyrosine supplementation blocks the depletion of catecholamine neurotransmitters that usually occurs with environmental stress.<10>  L-Tyrosine has also been shown to promote catecholamines, especially the dopamine that is needed for focus, memory and cognition.<11>

Brain Protection

L-Tyrosine has been shown in animal studies to help suppress the production of stress hormones in the brain, which researchers have suggested may combine with its brain chemical support to shield the brain from the adverse effects of stress.<12>

Mind Lab Pro® Stack Strategy: N-Acetyl L-Tyrosine + Rhodiola Rosea for Brainpower Under Pressure

L-Tyrosine's brain-boosting activity has been shown to be more pronounced during high-intensity cognitive tasks than relaxed cognitive tasks.<13> Rhodiola rosea's adaptogen activity helps regulate stress responses to maintain clear, fast mental processing during pressure-filled situations.

  • Together in Mind Lab Pro®, N-Acteyl L-Tyrosine and Rhodiola rosea supply complementary support for superior cognitive function under demanding, distracting and stressful scenarios -- forming a powerful nootropic duo for dynamic, competitive and high-performance individuals.

*The statements on this page have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent disease.


  1. http://www.macses.ucsf.edu/research/allostatic/catecholamine.php
  2. Harris R. Lieberman, et al. The catecholamine neurotransmitter precursor tyrosine increases anger during exposure to severe psychological stress. Psychopharmacology (Berl). 2015; 232(5): 943–951.
  3. Liu L, et al. Simultaneous determination of catecholamines and their metabolites related to Alzheimer's disease in human urine. J Sep Sci. 2011 May;34(10):1198-204.
  4. Spivak B, et al. Circulatory levels of catecholamines, serotonin and lipids in attention deficit hyperactivity disorder. Acta Psychiatr Scand. 1999 Apr;99(4):300-4.
  5. Jongkees BJ, et al. Effect of tyrosine supplementation on clinical and healthy populations under stress or cognitive demands--A review. J Psychiatr Res. 2015 Nov;70:50-7.
  6. Mahoney CR, et al. Tyrosine supplementation mitigates working memory decrements during cold exposure. Physiol Behav. 2007 Nov 23;92(4):575-82. Epub 2007 May 22
  7. Deijen JB1, Orlebeke JF.Effect of tyrosine on cognitive function and blood pressure under stress. Brain Res Bull. 1994;33(3):319-23
  8. Thomas JR, et al.Tyrosine improves working memory in a multitasking environment.Pharmacol Biochem Behav. 1999 Nov;64(3):495-500.
  9. Neri DF, et al.The effects of tyrosine on cognitive performance during extended wakefulness.Aviat Space Environ Med. 1995 Apr;66(4):313-9.
  10. Lieberman H. Tyrosine and Stress: Human and Animal Studies. Institute of Medicine (US) Committee on Military Nutrition Research; Marriott BM, editor. Washington (DC): National Academies Press (US); 1994.
  11. Jongkees BJ, et al. People are different: tyrosine's modulating effect on cognitive control in healthy humans may depend on individual differences related to dopamine function. Front Psychol. 2014; 5: 1101.
  12. Reinstein DK, Lehnert H, Wurtman RJ. Dietary tyrosine suppresses the rise in plasma corticosterone following acute stress in rats. Life Sci. 1985 Dec 9;37(23):2157-63
  13. Lorenza S. Colzato, et al. Working Memory Reloaded: Tyrosine Repletes Updating in the N-Back Task. Front Behav Neurosci. 2013; 7: 200

These statements have not been approved by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

This article is an opinion and explanation of current research given by the author. It is not an expression of a medical diagnosis or treatment and should not be relied on as such.

Mind Lab Pro® Universal Nootropic™

Mind Lab Pro® is the world's first Universal Nootropic™ – formulated to promote a healthy, peak-performing mindstate known as 100% Brainpower™.

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The statements on this page have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent disease.