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Mind Lab Pro® Ingredients

11 research-backed nootropics

 
Citicoline Cognizin

Citicoline 250 mg
as Cognizin®

Cognizin
  • Brain Regeneration
    Brain Regeneration
  • Brain Circulation
    Brain Circulation
  • Brain Protection
    Brain Protection
  • Brain Energy
    Brain Energy
  • Brain Chemicals
    Brain Chemicals

Brain Bioactivities: Citicoline helps energize brain cells while optimizing the neural electrical impulses that power all thought. Citicoline also helps synthesize phosphatidylcholine (PC), the major phospholipid found in brain cell membranes. In combining brain energy + phospholipid synthesis, citicoline may be uniquely qualified for the intensive task of brain cell regeneration and repair. Citicoline also supports neurotransmitters, including acetylcholine, while supplying brain-protective antioxidant activity.

Potential Nootropic Benefits: Energizes and enhances mental performance without the crash of stimulants. Cognizin® Citicoline has been shown in human research to promote mood balance, memory, attention, focus and concentration. Long term, it may help maintain healthy brain function against age-related structural changes and mental decline.

  • Mind Lab Pro®’s Cognizin® is a patented citicoline form with benefits for brain energy, mental performance and recall backed by multiple human clinical trials.
Citicoline Graph

Cognizin® Citicoline has been shown to boost brain cell membrane formation by 26% and brain energy by 13.6%.

Silveri MM, et al. Cognizin® Citicoline Increases Brain Energy (ATP) by 14% and Speeds up Formation of Brain Membranes by 26% in Healthy Adults. Soc. Neurosci, San Diego, CA

Phosphatidylserine

Phosphatidylserine (PS) 100 mg

as Sharp PS® Green from Sunflower Lecithin

Sharp-PS® Green
  • Brain Regeneration
    Brain Regeneration
  • Brain Protection
    Brain Protection
  • Brain Energy
    Brain Energy
  • Brain Chemicals
    Brain Chemicals

Brain Bioactivities: PS is a phospholipid compound that comprises 15% of the brain’s fats. It is concentrated in brain cell membranes, where it helps maintain fluidity, optimizes receptors, and promotes neurotransmitters like acetylcholine and dopamine. It supports brain cell energy production by enhancing glucose metabolism. It may increase nerve growth factor (NGF) to support brain cell creation, maintenance and repair. PS also helps immune cells dispose of damaged, toxic brain cells, sparing neighboring brain cells from collateral damage.

Potential Nootropic Benefits: PS may sharpen memory, slow cognitive decline, and promote a positive-minded outlook. It has shown promise for helping elderly with brain degeneration, apparently slowing the progression of memory loss while helping with mood, anxiety, socialization and mental clarity. As a result, PS is the only nootropic with an FDA-qualified claim for reducing cognitive decline risk.

  • Mind Lab Pro®’s Sharp PS® Green is a soy-free, non-GMO, eco-friendly phosphatidylserine derived from sunflower lecithin.
Phosphatidylserine (PS) Graph Phosphatidylserine (PS) Graph

Phospholipids like PS decline in the brain with age, along with many measures of cognitive performance.

Söderberg M, et al. J Neurochem. 1990 Feb;54(2):415-23l; http://ns.umich.edu/Releases/2001/Aug01/r081301a.html

Bacopa Monnieri

Bacopa Monnieri 150 mg

Full-spectrum extract, standardized for 24% bacosides, calibrated to supply 9 bioactives

  • Brain Circulation
    Brain Circulation
  • Brain Protection
    Brain Protection
  • Brain Chemicals
    Brain Chemicals

Brain Bioactivities: Bacopa’s active bacosides are antioxidants that enhance other brain antioxidants, including superoxide dismutase (SOD) and glutathione peroxidase (GPx). This synergistic antioxidant activity helps protect brain cells from the age-accelerating effects of free radicals. Bacosides also promote acetylcholine, GABA and serotonin – all brain chemicals tied to focused thinking, clear memory and healthy mood.

Potential Nootropic Benefits: Bacopa has strong ties to memory performance and a long association with new learning and retention. Human research shows Bacopa may slow the rate of forgetting newly acquired knowledge. Researchers have also suggested it may accelerate mental processing, optimize cognition under stress, and promote relaxation.

  • Mind Lab Pro®’s 24% bacosides Bacopa monnieri supplies the herb’s 9 most active nootropic bacoside compounds.
Bacopa Monnieri Memory Graph
Barbhaiya et al., J. Pharmacol. Toxicol., 2008, 3: 425-434
Bacopa Monnieri Recall Graph Bacopa Monnieri Learning Graph
Morgan and Stevens. J Altern Complement Med., 2010, 16 : 753-759

Mind Lab Pro®’s Bacopa monnieri has been shown to enhance delayed recall memory, immediate recall memory and learning in clinical research.

Lion's Mane Mushroom

Lion’s Mane Mushroom 500 mg

Full-spectrum extract with active hericenones and erinacines

  • Brain Regeneration
    Brain Regeneration
  • Brain Protection
    Brain Protection

Brain Bioactivities: The only mushroom that supports brain health, Lion’s Mane supplies active nootropics called hericenones and erinacines. Animal research suggests Lion’s Mane stimulates Nerve Growth Factor (NGF) production, which may help with neural regeneration and myelin nerve sheath synthesis. Optimized NGF may support brain plasticity for storage of new learning and memories, as well as promoting robust brain cell replication and healthy brain cell membrane function.

Potential Nootropic Benefits: A double-blind, placebo-controlled trial linked Lion’s Mane Mushroom to significant cognitive improvements in adults aged 50-80 with mild cognitive impairment. Clinical trial researchers have also suggested that Lion’s Mane may help to maintain mood balance.

  • Mind Lab Pro®’s full-spectrum Lion’s Mane Extract supplies all the mushroom’s active constituents, including brain-boosting hericenones and erinacines.
Lion's Mane Mushroom Graph

Lion’s Mane Mushroom (Yamabushitake) has been linked to significant cognitive improvements that declined after supplementation stopped.

Mori K, et al. Phytother Res. 2009 Mar;23(3):367-72.

Maritime Pine Bark Extract

Maritime Pine Bark Extract 75 mg

standardized for min. 95% proanthocyanidins

  • Brain Protection
    Brain Protection
  • Brain Circulation
    Brain Circulation
  • Brain Regeneration
    Brain Regeneration
  • Brain Energy
    Brain Energy

Brain Bioactivities: Supplies a potent complex of proanthocyanidin antioxidants that can cross the blood-brain barrier and help to neutralize the damaging effects of toxic free radicals that are concentrated in the brain. Pine Bark Extract’s proanthocyanidins also signal for the release of nitric oxide (NO), which relaxes blood vessels and increases blood flow to the brain – enhancing delivery of brain-energizing oxygen and glucose. The bark’s additional proanthocyanidin bioactivities combine to provide multi-pathway brain regeneration support that has been suggested to help reverse age-related cognitive decline.

Potential Nootropic Benefits: Pine bark extract’s proanthocyanidin compounds are suggested to enhance mental energy, attention, learning and focus in the short term; and maintain memory, mental clarity and brain health in later years.

  • Mind Lab Pro® uses the strongest pine bark form on the market today: Standardized for a minimum of 95% active nootropic proanthocyanidins
Maritime Pine Tree

Maritime pine trees adapted to their salty, windswept environment by developing a powerful protective antioxidant complex in their bark.

N-Acetyl-L-Tyrosine

L-Tyrosine 175 mg

as N-Acetyl-L-Tyrosine (NALT)

  • Brain Protection
    Brain Protection
  • Brain Chemicals
    Brain Chemicals

Brain Bioactivities: L-Tyrosine is an amino acid compound used to synthesize catecholamine neurotransmitters involved in memory, mood and mental processing, including dopamine, epinephrine, and norepinephrine. Animal research suggests L-Tyrosine may counter the impact of brain stress, potentially helping to support synthesis of neurotransmitters that are depleted by high-pressure thinking.

Potential Nootropic Benefits: Human clinical research has suggested L-Tyrosine may help to promote working memory under multitasking conditions and optimize mental performance under high stress, fatigue and sleep deprivation. In addition to its reputation as a nootropic for maintaining mental performance under stress, L-Tyrosine has recently drawn interest as an attention and focus-oriented nootropic.

  • Mind Lab Pro®’s N-Acetyl-L-Tyrosine is the best form for brain health: Easy to absorb and bioavailable, it delivers more nootropic activity than plain Tyrosine.
Tyrosine

L-Tyrosine was found to enhance mental performance with greater benefits recorded as tasks progressed from easier (1-BACK) to more difficult (2-BACK).

Colzato LS, et al. Front. Behav. Neurosci., 16 December 2013.

L-Theanine

L-Theanine 100mg

as Suntheanine®

Suntheanine
  • Brain Waves
    Brain Waves
  • Brain Protection
    Brain Protection
  • Brain Chemicals
    Brain Chemicals

Brain Bioactivities: L-Theanine helps to increase activity of alpha brainwaves, which are associated with a state of wakeful relaxation and enhanced creativity. It seems to settle excitable neurotransmitters while promoting calming neurotransmitters like serotonin, dopamine and GABA. L-Theanine has been suggested by researchers to modulate the brain’s ”attention circuitry.” It may also protect neurons from damage, potentially helping to maintain clear thinking during the aging process.

Potential Nootropic Benefits: L-Theanine may instill a state of calm, relaxed tranquility while simultaneously sharpening attention, alertness and focus. It is used for studying, new learning, creative problem solving, art, or other tasks that require quiet contemplation. L-Theanine also helps to reduce the harsh jittery side effects of caffeine.

  • Mind Lab Pro®’s premium Suntheanine® supplies 100% pure L-isomer-Theanine. Suntheanine® has been shown in human clinical research to enhance Alpha brainwaves.

L-Theanine shows nootropic promise in numerous human clinical trials

L-Theanine Dose Subjects & Design Researchers’ Observations

L-Theanine 50 mg, L-Theanine 200 mg

8 Female university students) (age: 18-22 y), placebo-controlled, three-way crossover trial

Reported dose-dependent increase in alpha activity in occipital and parietal brain areas 30 min after consumption of L-theanine compared with placebo.

L-Theanine 200 mg

20 healthy males (age range 18–30 y), placebo controlled

L-theanine increased alpha brain wave activity in the occipital area, compared with placebo, among those with higher reported anxiety (p<0.05)

L-Theanine 50 mg

35 healthy young participants, randomized, placebo-controlled

Compared with placebo on EEG at 45, 60, 75, 90, and 105 min after ingestion, L-theanine 50 mg produced greater and increasing alpha activity (p<0.05)

L-Theanine 250 mg

15 participants (mean age 27.8 y), placebo-controlled

Attention-related alpha activity was greater and background alpha reduced for the L-theanine condition compared with placebo (significant attention modulation index, (p<0.05)

Bryan J. Nutr Rev. 2008 Feb;66(2):82-90.
Rhodiola rosea

Rhodiola Rosea 50 mg

standardized for min. 3% rosavins, 1% salidrosides

  • Brain Energy
    Brain Energy
  • Brain Chemicals
    Brain Chemicals
  • Brain Protection
    Brain Protection

Brain Bioactivities: Rhodiola is believed to stimulate and sustain cognition-critical neurotransmitters including norepinephrine, dopamine, and serotonin. It may further optimize these neurotransmitters by helping their transport across the blood-brain barrier. Rhodiola has acetylcholine-protective and antioxidant properties that may help with age-related decline. Most notably, Rhodiola strengthens mental resistance to stress by blunting release of stress hormones including cortisol. Research suggests rhodiola’s nootropic effects begin within 30 minutes and may last for up to six hours.

Potential Nootropic Benefits: As an herbal Adaptogen, Rhodiola helps strengthen mental + physical stress resistance while supporting brain energy – promoting clear, calm thinking under taxing conditions. Rhodiola is traditionally used to enhance mental processing, memory, learning, attention span, mood and work capacity. It also gained fame as a legal performance-enhancer among Russian Olympic biathletes and powerlifters.

  • Mind Lab Pro®’s Rhodiola is standardized for a minimum 3% rosavins and 1% salidrosides, ensuring effective levels of active nootropics in each capsule.
Rhodiola Rosea Graph

Rhodiola has been linked to dose-dependent mental energy benefits in human clinical research

Shevtsov VA, et al. Phytomedicine. 2003 Mar;10(2-3):95-105.

Vitamin B6

B6 2.5 mg
B9 100 mcg
B12 7.5 mcg

as BioGenesis™ nature-identical whole-food vitamins*

Biogenesis™
  • Brain Chemicals
    Brain Chemicals
  • Brain Circulation
    Brain Circulation
  • Brain Protection
    Brain Protection
  • Brain Regeneration
    Brain Regeneration

Brain Bioactivities: All B vitamins contribute to brain health, but most research focuses on B6, B9 and B12 due to their key role in homocysteine metabolism. High homocysteine levels and suboptimal B6, B9 and B12 intake are interconnected and modifiable risk factors for brain degeneration, cerebrovascular concerns, mood imbalance and cognitive decline. Supplemental B6+B9+B12 has been shown help balance homocysteine levels in a healthy range associated with sharp overall mental performance.

Potential Nootropic Benefits: Mind Lab Pro®’s B6+B9+B12 targets homocysteine as a synergistic trio, helping with mental performance concerns related to cognitive decline, brain aging, and poor blood flow to the brain. Vitamins B6+B9+B12 have also been shown to promote mood balance, mental energy, information storage and long-range brain health.

  • Some B-vitamins become harder to absorb with age. Mind Lab Pro®’s B6, B9 and B12 are in BioGenesis™ nature-identical form: Complexed with cofactors that enhance B-Vitamin absorption and ultimate B-Vitamin brain benefits in all populations.
B6+B9+B12 Reduces Homocysteine

Mind Lab Pro®’s B6+B9+B12 reduces homocysteine -- thereby promoting brain chemical synthesis and blood flow to the brain

B6+B9+B12 also support brain health by:

  • Promoting brain chemical production of monoamines
  • Supporting brain chemical conversion and utilization
  • Catalyzing brain energy metabolism
  • Maintaining the mood-balancing brain protector S−Adenosyl Methionine (SAMe)
  • Forming myelin, the fatty sheath that surrounds and protects all brain cells and nerves

*BioGenesis™ nature-identical vitamins and minerals are lab-grown via dual-organism cultivation that produces a complex of absorption-enhancing cofactors.

References