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Does Lion’s Mane Mushroom Make You Sleepy?

By Abigail Roberts | |

Lion’s Mane, also known as Yamabushitake, is a dietary mushroom that can be consumed in raw form or taken as a supplement. It is also a common ingredient in the best nootropics on the market today.

It's long been used in traditional Chinese medicine, as it is known to have a number of health benefits, including cognitive enhancement and anti-inflammatory properties1.

In this article, we will answer all your burning questions on lion’s mane such as:

  • What are the benefits of taking lion’s mane?
  • How should you take lion’s mane?
  • Does lion’s mane make you sleepy?
  • Are there any side effects to taking lion’s mane?

Read on to find out all you need to know!

Benefits of Lion’s Mane Mushroom

Many of the findings on lion’s mane stem from animal-based research and small clinical trials, though the studies so far appear to be promising!

Here are some of the potential health benefits of lion’s mane:

  • Cognitive function

Studies show that lion’s mane can enhance cognitive function and reduce cognitive decline in older individuals, particularly by stimulating the synthesis of nerve growth factor (NGF), which in turn promotes overall brain health.

These findings might support the idea that lion’s mane may be beneficial to those suffering with diseases such as Alzheimer’s, though further human studies are needed to confirm this.

  • Anti-inflammatory

Chronic inflammation is believed to be the root cause of many chronic illnesses such as heart disease, cancer, and autoimmune disorders. Lion’s mane is known to have anti-inflammatory and antioxidant properties that may help reduce the impact of these conditions.

  • Protect against digestive ulcers

An in vitro study has shown that lion’s mane reduces the growth of H. pylori, a bacteria that can be one of the causing factors of stomach ulcers if it overgrows. Therefore, lion’s mane may help protect the stomach lining from ulcers!2

  • Anti-depressant and anxiolytic properties

Some studies have suggested lion’s mane may help ease mild symptoms of anxiety and depression. Significant improvements in anxiety and concentration were noted upon the consumption of lion’s mane mushroom, as well as possible improvements in sleep quality3.

Reducing anxiety and stress is usually one of the best ways to promote sleep quality. Many people struggle to get to sleep at night because that is when their anxiety becomes most acute. By reducing anxiety, lion's mane mushroom can help you get a better night's sleep, thus making you less sleepy the following day.

  • Reduction in menopausal symptoms

In one study, menopausal women found that the daily consumption of lion’s mane for one month helped reduce feelings of irritation and anxiety associated with menopause4.

Many women find that their sleep quality gets completely ruined during menopause; they wake up early, struggle to get to sleep at night, and spend hours tossing and turning. By reducing menopausal symptoms, Lion's Mane Mushroom can help improve sleep quality.

How to take Lion’s Mane Mushroom

Lion’s mane can be consumed in many forms, such as raw, cooked, or as a tea or supplement - we, of course, would recommend our Mind Lab Pro supplement!

As there are limited human studies, the optimal dose isn’t confirmed. However, it appears that 1,000mg thrice daily (total 3g of lion’s mane extract per day) is an effective dose5.

Does Lion’s Mane Mushroom make you sleepy?

There is some very promising research emerging on the health benefits of lion’s mane, but does it make you sleepy? And are there any other side effects?

In short - no, lion’s mane mushroom will not make you sleepy. However, due to the noted benefits on anti-anxiety and possible improvements in sleep quality, it may be a good idea to take lion’s mane before bedtime as part of your unwinding routine!

Side effects of Lion’s Mane Mushroom

As research is still in the preliminary stages, it’s not known what the long-term effects of lion's mane supplementation are. Though there have been no reported side effects so far.

That being said, there have been some reports of allergy-related symptoms after consumption of lion’s mane, so it’s important to ensure you’re not allergic to mushrooms before taking it.

As always, consult your doctor before taking any new supplement!

Key takeaways:

  • Lion’s mane mushroom has been consumed as part of traditional Chinese medicine and culinary for many years
  • The health benefits of lion’s mane include cognitive enhancement, anti-inflammatory, and potential anti-depressant and anxiolytic properties
  • Research is still in its early days but appears promising!
  • Lion’s mane does not make you sleepy and has no other reported side effects3  


  1. Patel. Lion’s Mane. Examine.com. 2021
  2. Jiang S, Wang S, Sun Y, Zhang Q. Medicinal properties of Hericium erinaceus and its potential to formulate novel mushroom-based pharmaceuticals. Appl Microbiol Biotechnol. 2014 Sep;98(18):7661-70.
  3. Patel. Lion’s Mane. Examine.com. 2021
  4. Patel. Lion’s Mane. Examine.com. 2021
  5. Patel. Lion’s Mane. Examine.com. 2021

These statements have not been approved by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

This article is an opinion and explanation of current research given by the author. It is not an expression of a medical diagnosis or treatment and should not be relied on as such.

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