Dosages of Lion’s Mane vary, and at the time of writing, there are no optimal dosage recommendations.

More human studies are needed to develop comprehensive dosage guidelines aimed at various health outcomes. However, many safe and effective doses have been noted in existing research!

Here, we will discuss lion’s mane and the safe recommended doses that have been noted in relation to desired outcomes, such as relieving symptoms of anxiety and depression, improving cognitive function, and its use as a powerful nootropic.

Firstly, a brief overview of Lion’s Mane and its health benefits:

Lion’s mane (hericium erinaceus), also known as Monkey’s Head, Pom Pom Blanc, or Satyr’s beard for its distinctive shaggy-like appearance, is an edible mushroom belonging to the tooth fungus group.

Lion’s mane has been used for centuries in traditional Chinese medicine and cuisine for the many health benefits it holds thanks to the effective bioactive compounds it contains.

Some of the key health benefits include:

  • Improving cognitive function
  • Anti-inflammatory and antioxidant properties
  • Anti-depressant and anxiolytic properties
  • Protecting against digestive ulcers

You can consume lion’s mane in its original form incorporated into recipes, steeped in tea, or as a supplement in powder, capsule, or liquid form.

Lion’s Mane General Dosage

It has been reported that effective doses vary from 500mg-3000mg (96% purity extract). This dose appears to be safe and results in minimal side effects for those not allergic to mushrooms.1

Lion’s Mane Dosage: Reduce Symptoms of Anxiety and Depression

In one study which looked at the effect of lion’s mane mushroom on symptoms of anxiety and depression, thirty females were randomly assigned to one of two groups. One group received cookies containing 0.5g powdered lion’s mane, and the other group were given a placebo.2

Over the course of 4 weeks, feelings of irritation and anxiousness were significantly lower in the group that received lion’s mane. These results suggest that a minor intake of lion’s mane in powdered form may be an effective dose in easing mild symptoms of anxiety and depression!

Lion’s Mane Dosage: Improving Cognitive Function

An interesting study was conducted on 50 to 80-year-old Japanese men and women who had been diagnosed with mild cognitive impairment.3

Thirty subjects were divided into two groups - one group took four 250mg tablets containing 96% lion’s mane dry power three times daily for 16 weeks, the other group were given a placebo.

Over the course of the trial, the lion’s mane group showed significant improvements in cognitive function compared with the placebo group. Upon termination of the intake, the subjects were observed for a further 4 weeks, at which their cognitive function decreased.

The result of this study shows that lion’s mane is effective in improving mild cognitive impairment, and cognitive function actually declines upon cessation of intake!

Lion’s Mane Mushroom: A Powerful Nootropic

To really optimise your brain health and function, it’s best to take lion’s mane as part of a powerful formula, combining other cognitive-enhancing nootropics.

In Mind Lab Pro, there is 500mg of lion’s mane, a proven effective dose for optimizing a wide array of cognitive functions as part of this formula!

Can You Take Too Much Lion’s Mane?

In short, it would be difficult to overdose on lion’s mane. Some studies have used doses of up to 3,000mg which have been marked safe and resulted in minimal side effects.

However, more does not always mean better! We strongly advise following the specific dosage guidelines on the product you’re using.

There have been no noted side effects from taking lion’s mane, unless you have an allergy to mushrooms. Though, as always, we recommend consulting your doctor if you’re thinking of taking a new supplement!

Final Thoughts

Doses of lion’s mane may vary, but in most supplements, you will find it to be an effective dose.

Research is yet to be conducted to determine an optimal intake, but for now it appears you can reap the many health benefits of lion’s mane with the doses currently noted!


  1. K. Patel. Lion’s Mane. 2021
  2. Nagano M, Shimizu K, Kondo R, Hayashi C, Sato D, Kitagawa K, Ohnuki K. Reduction of depression and anxiety by 4 weeks Hericium erinaceus intake. Biomed Res. 2010 Aug;31(4):231-7.
  3. Mori K, Inatomi S, Ouchi K, Azumi Y, Tuchida T. Improving effects of the mushroom Yamabushitake (Hericium erinaceus) on mild cognitive impairment: a double-blind placebo-controlled clinical trial. Phytother Res. 2009 Mar;23(3):367-72.